[1-Methoxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone
نویسندگان
چکیده
Methyl-ation of [1-hy-droxy-3-(pyridin-2-yl)indolizin-2-yl](pyridin-2-yl)methanone was performed via metalation with potassium tert-butano-late in toluene and a subsequent metathesis reaction with methyl iodide yielded the yellow title compound, C(20)H(15)N(3)O(2). The substituents at the indolizine unit are twisted [the indolizine ring system makes dihedral angles of 34.67 (7) and 77.49 (5)°, respectively, with the pyridyl and pyridinoyl rings] with single bonds between the central unit and the attached pyridine ring [1.459 (3) Å] and the pyridinoyl group [1.483 (3) Å]. There are no classical hydrogen bonds in the crystal structure.
منابع مشابه
catena-Poly[[[bis(acetato-κ2 O,O′)aquacadmium]-μ-[(pyridin-3-yl)(pyridin-4-yl)methanone]-κ2 N:N′] dihydrate]
In the title complex, {[Cd(CH(3)COO)(2)(C(11)H(8)N(2)O)(H(2)O)]·2H(2)O}(n), the Cd(II) ion adopts an O(5)N(2) penta-gonal-bipyramidal coordination geometry with four acetate O atoms and one water O atom at the equatorial sites and two pyridine N atoms at the axial sites. The (pyridin-3-yl)(pyridin-4-yl)methanone ligand acts in a μ(2)-bridging mode, linking the metal atoms, leading to an infinit...
متن کامل(5-Benzoyl-2-methyl-4-{[1-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl]methoxy}-1-benzofuran-7-yl)(phenyl)methanone
The crystal structure of the title compound, C(31)H(22)N(4)O(4), features weak C-H⋯O inter-actions. The dihedral angle between the fused benzene and furan rings is 2.49 (15)°, while that between the triazole and pyridine rings is 10.23(18)°.
متن کاملcatena-Poly[(dichloridozinc)-μ-bis(pyridin-3-yl)methanone-κ2 N:N′]
In the title polymer, [ZnCl(2)(C(11)H(8)N(2)O)](n), the Zn(II) atom lies on a twofold rotation axis and has a distorted tetra-hedral ZnCl(2)N(2) geometry involving two chloride donors and two N-atom donors from μ(2)-bridging bis-(pyridin-3-yl)methanone ligands, which also have twofold symmetry. A zigzag chain structure is formed, extending along (001). Each chain is surrounded by three others w...
متن کاملSynthesis and QSAR evaluation of 2-(substituted phenyl)-1H-benzimidazoles and [2-(substituted phenyl)-benzimidazol-1-yl]-pyridin-3-yl-methanones.
A series of 2-(substituted phenyl)-1H-benzimidazole (1-10) and [2-(substituted phenyl)-benzimidazol-1-yl]-pyridin-3-yl-methanone (11-19) derivatives were synthesized and tested in vitro for their antimicrobial activity. The results of QSAR investigation indicated the importance of molecular descriptors, dipole moment (mu), log of octanol water partition coefficient (logP) and second order molec...
متن کاملA second monoclinic polymorph of (E)-phenyl(pyridin-2-yl)methanone oxime
The title compound, C(12)H(10)N(2)O, a second monoclinic poly-morph of (E)-phen-yl(pyridin-2-yl)methanone oxime crystallizes in the space group P2(1)/n (Z = 4). The previously reported polymorph [Taga et al. (1990 ▶). Acta Cryst. C46, 2241-2243] occurs in the space group C2/c (Z = 8). In the crystal, pairs of bifurcated O-H⋯(N,O) hydrogen bonds link the mol-ecules into inversion dimers. The dim...
متن کامل